xplac3b0

Not the op, but at least from what I've seen often multiple readings are done in metabolomics to help establish the patients baseline so as you do longitudinal studies you can then determine true statistical deviation. Metabolism is constantly active and can deviate a lot internally(ie fasting vs non fasting sample collection can have a huge impact on variability of analytes), so doing the frequent blood draw helps reduce that noise.

Are you doing this off a high res ms1 qtof or are you using an orbi and collecting ms2 or? Are you doing quant and this is all an mrm panel? Are you doing multiple runs to hit multiple species(ie pos, negative on both c18 and hilic)? Did you guys build out the library using IROA or how was the workflow built out? Just curious as I'm starting to look at expanding passed my proteomic runs into metabolomics for my own research. Thanks for taking the time to introduce people on reddit to metabolomics!

Edited since I saw you said you do 650 analytes in another response.

I totally agree with you on the consumer. Their plans seem really arbitrary in the cost for the return and the number of tests. Not sure how they came up with it but hopefully op will give us some response.