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teidou9 karma

Thank you for doing this AMA.

Have you had any problems with excessive bleeding?

One of my colleagues found that poisoning mitochondria impairs platelets function - I am curious whether there is a tendency to bleed when you have partial function.

teidou2 karma

Delta granule storage deficiency is lack of the stuff platelets release in order to initiate clotting. I believe what granules there are release OK, just too few of them.

The defect seen when mitochondria are poisoned (in a test tube) is lack of ability to release those granules.

So, I think the two are definitely related.

How low is your platelet count? (If you prefer to PM, OK too...)