Hi, I wonder about psychoactivity of edibles. Whole lot of cannabis websites are claiming that edibles are more potent (which I would agree on) and they support this claim by suggesting 11-OH-THC is more psychoactive and, of course, after consumption THC undergoes metabolization to 11-OH-THC. Since I did not manage to find any relevant studies either behaviour or pharmacological (affinity, EC50,etc), I would like to ask what are your thoughts on this topic? Or could it be that smoking is just bad way to consume weed (high temperature, destruction of THC)?
ondrastuchl1 karma
Hi, I wonder about psychoactivity of edibles. Whole lot of cannabis websites are claiming that edibles are more potent (which I would agree on) and they support this claim by suggesting 11-OH-THC is more psychoactive and, of course, after consumption THC undergoes metabolization to 11-OH-THC. Since I did not manage to find any relevant studies either behaviour or pharmacological (affinity, EC50,etc), I would like to ask what are your thoughts on this topic? Or could it be that smoking is just bad way to consume weed (high temperature, destruction of THC)?
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