ndevito1

UPVOTE

THIS SHOULD NEVER DIE

Steve, you spoke to my intro to global health class when I was a freshman in college about six years ago. Your story was one of many from that class that got me interested in global health and inspired me to hopefully pursue it as a career. I believe you said you have probably subjected yourself to thousands if not millions of mosquito bites as a part of this research. Glad they weren't in vein! (pun very intended)

Glad to hear you have made so much progress with the vaccine!

My questions:

• What are you future plans for dealing with the IP and costing of the drug as you move forward to a hopefully very successful rollout? Obviously there are potentially competing interests for something like this in terms of access vs profit. Do you take any lessons from the HIV/AIDS epidemic, TB epidemic or the various neglected diseases in designing how you hope people will access this vaccine?

• I imagine you might be able to get some sort of expedited review for this as the FDA has recently been keen on speeding on the process on certain breakthrough medications such as this. If you can get the USG to buy into this we could see some significant coverage rather quickly. What are your plans on the regulatory front?

• Also as a small, independent company, does that offer you and leeway that the large pharmaceutical and biotech companies do not offer or is it more of a hinderance? Do you believe this research will suffice for a phase I trial of the vaccine?

• Are there any worries about resistance with your mechanism of action?

Thanks!

Edit: Expanded on my Qs! So many Qs!

Ithaca is a pretty cool place to go to college. Lots of outdoorsy stuff if that's your thing. Plenty to do around campus. I suppose "normal people" do lots of things and luckily there are lots of things to do...

Amazing! Thank you both for your answers as well as your continued commitment to this vaccine. I will be rooting for you every step of the way.

What was the last major thing you failed at?