midfield99

I'm not a huge fan of durian, it's definitely a very unique taste. But I did once have some durian ice cream that was really good. The durian added a rich, custardy flavor to the ice cream.

I heard you can make decent money teaching English in non-western countries like China, Japan, and Thailand. I have classmates who have done that and they got paid what sounded like a middle class salary, they were able to afford comfortable apartments, and had extra money every month. For example this job (http://www.goabroad.com/providers/aeon/programs/teach-english-in-japan-with-aeon-corporation%21-1879 ) offers a teaching position in Japan with a 270,000 yen monthly salary ( around $2,714)and a subsidized apartment of 55,000 yen a month (around $553). The only problem is I'm not sure how much your loan payments are and if some of the jobs would give you enough money to pay off the loans. And I don't believe you can really find good jobs teaching English in western countries. But usually the only qualification for teaching english in non-western countries is a four year degree.

Our answer is to allow people to control, but not outright own, URLs. We think this will result in the names being most likely to return what people are actually looking for. ...

Also worth clarifying: if you just want a URL you always own, you can do this by publishing an exact stream hash (similar to a BitTorrent magnet link). ONLY the user-friendly, English URLs are awarded via this system. Additionally, URLs take significant time to change. The original owner, and the community at large, have weeks to respond to a contested claim.

It sounds like an interesting experiment, but I think this is a horrible design choice. People search for urls by english names, not hard to memorize hashes. This will definitely confuse viewers when their favorite channel is bought out by someone else. And your solution would be like asking people to browse the internet with ip addresses instead of urls.

On average the most out of pocket anyone has paid is around $40.

I'm assuming that the list price is much higher than that. And that the low out of pocket cost is because most of the drug cost is paid by insurers. And I'm assuming the per unit cost to manufacture the medication is low, so they can afford to waive fees if people don't have insurance. So I don't think they are charging anywhere near $40 per patient, and insurance companies are responsible for the majority of the gross profit.

Plus the drug received significant monetary support from the FDA. The FDA wants to encourage the development of drugs for rare diseases, so they have a program where they can give priority reviews to companies that develop those drugs. These priority reviews allow the company to cut in line and get a drug reviewed faster. But these reviews don't apply to a specific drug, they can apply to any drug. The company can even sell it. This faster review is really valuable if you are a gigantic drug company developing the next blockbuster drug. The priority review that came with Impavido sold for $125 million. I'm definitely not saying this is a bad thing. The FDA doesn't give a lot of these out, and $125 million probably does a lot to encourage research into rare diseases.

I'm definitely not criticizing his company or drug. I think its definitely a good think that he is able to provide a life-saving drug to people who are ignored by other companies. And I definitely don't think he is price-gouging anyone. But companies can't really afford to through away hundreds of millions on drugs that won't make money, and $40 per person does nothing for their expenses.

What's the reason of having a goal of $10k/month? That number doesn't have meaning if it isn't attached to a base. Also, I noticed you referenced notional accounts of $500,000. If that number is being used to calculate the target goal of $10k/month, then you are wanting to return over 25% a year. That seems very aggresive, especially if you are making conservative investment choices.