lrrc49

My understanding is that the cannabinoid receptors for CB1, CB2, and GPR55 need to be present in the tumor cell to cause apoptosis. Given tumor heterogeneity what are the odds of these receptors being expressed on every cancer cell?

Given that information it appears like cannabinoids are capable of inducing apoptosis in cells that re-express these receptors, but what about the cells that just don't? Would that just leave behind a more drug resistant tumor?

any updates on necessary receptor status to induce apoptosis/has our understanding changed?

How many corporate CEOs, politicians, and billionaires can you link to being basically child molestors?

Check out the work of David Meiri

https://www.researchgate.net/profile/David-Meiri

His research into what cannabinoids do what and in what combination made me realize i could stop writing a grant along the same lines. He and ergo israel are way ahead when it comes to what combinations of cannabinoids do in various disease states.