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lifesaver13bsa1 karma

What brain region are they stimulating? Ventral capsule, nucleus accumbens? I ask because I am part of a research team that is working to figure out the neural mechanisms of DBS. We focus on understanding why and how DBS to the subgenual cingulate works in severe, intractable depression (and also why doesn't it work in some situations)? As a cognitive neuroscientist on the team, my part of the research involves trying to understand how stimulating a particular part of the brain affects other regions of the brain. Current findings suggest that rather than just stimulating one brain region, DBS produces downstream effects in brain regions connected to the DBS region. So the issue of 'targeting' certain brain regions has to do with both what that region does and what regions that are connected to it do. It would be great to hear your thoughts on the sorts of feelings/sensations you had when you first noticed that the DBS was on and working, as well as any feelings/sensations you have as the DBS is left on chronically.