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la_peregrine600 karma

Actually it depends on how you write it. Tell the school about the hundred of hours you spent babysitting/taking care of grandma/ having a side job to help pay the bills. How has this impacted you (and not just the I couldn't devote time to playing tennis)? Maybe your grandpa was a war veteran and his ear stories got you interested in history. Maybe your grandma talked about how she had dreams to become an engineer but she met sexism and that got you to reflect on social justice so now you want to be a lawyer or you want to keep pushing and do the things she couldn't so now you want to become a (insert male dominated field/profession) here. Maybe you tried to understand the economics of running a fast food place and why fast food workers are paid so little which sparked your interest in business.

You spent the time practicing these things. Maybe they are not your typical clubs. Maybe they are not glamorous or desirable or cool. Maybe they are in fact activities that motivate you to do more. But you did spend the time doing these things so tell us what that means to you and what you learned.

Maybe you learned to multitask and you were working on memorizing the Krebs cycle while flipping burgers. Maybe you figured out how to optimize the process so you can be more efficient. Maybe you reflected the unfairness if your position and made plans to never be in that position again. Maybe you learned how to lead a team. Or how to be patient with people.

Reflect on what you had to do. Then discuss that.

la_peregrine48 karma

I am rather unappreciative of the carelessness of the numbers here.

Presenting 400 per test vs 109 per month would make it seem that you are roughly 4 times cheaper. But since you are testing only 6 times per year which means you are charging 218 per test, you are only roughly 2 times cheaper.

I also do not think you quite address the question, and I'd really like it if you did.

Could you answer the question why we need an answer every 2 months instead of say every 1 yr or 5 yrs or 10 yes? Because your test being twice cheaper while measuring more stuff doesn't explain why we need so many measurements per year. It would be nice to know what making these measurements on say every 10 years give, then what more you'd learn if you test every 5 yrs, every 1 yr, every 6 month, and finally why it is worth it every other month as you are advocating here.

la_peregrine21 karma

It doesn't. This is why companies do not fix things. The appropriate punishment would be prison time for everyone who knew and covered up, seising the management salary and stock options that they received for the duration of the problem, the closure of the company and reselling the factory to a different company who will be required to bring it up to code and employ the same worker for 1 year with the sales proceeds going out to the victims with minimal lawyer/administrative fees covered.

Only when you make the cover up more expensive that the fix will shit get fixed...

la_peregrine15 karma

Then this is not a product ready for consumers but a pay us so we can do science and we will share your results with our speculations.

I fully understand why this profits the company...I am still trying to understand why this is good for the consumer. I still do not see how this isn't another Theranos be it intentionally or not.

la_peregrine15 karma

I appreciate your response.

we instruct users to always take their sample in the morning, after at least 8-10 hours of overnight fasting. This is an established procedure to remove unwanted variation, and has been used in many large-scale research studies around the world.

...

Now, admittedly, whether this needs to happen every 3 months, every 2 months, or every month is still up for debate. That’s also why we offer different packages, where people who are more skeptical can start with a smaller version, and people who are very interested in a fine-grained analysis of their personal profiles can go for the premium packages.

True and if this was IAmA about cool research or non-profit research study I'd accept it. However, this is an IAmA about "iollo (our startup) to give you a new way to understand your health and aging by measuring 500 blood metabolites." From that perspective I expect you to have a handle on what would a consumer get with what frequency of studies. This is definitely not something that the average consumer should be expected to do. Furthermore, to make recommendations you have to know on what scale variability is relevant for what condition. For example, every two months is vastly inadequate to monitor bun and creatinine for CKD purposes but is overkill for the average person concerned with general aging or some unrelated condition. Even young male with proteinuria suggesting monitoring for IgA nephorpathy, the standard of care is not a test every 2 months but much less. So every 2 months may not be a premium product if every 2 months is unnecessary and does not provide information. To provide a different example of the concept -- if i am interested in weather then atmospheric moisture level every 15 min may be useful but if I am interested in long term climate, such measurement will be noise and the first step would be to average it out.

It is against this subreddit rules to ask the same question but to me you have NOT ANSWERED THE QUESTION on what time scales do the different markers that you measure and the different conditions that you make recommendations about require monitoring.