What is your opinion of George Shaw's (a leader whose opinon I trust) observation that even with neutralizing antibodies present, HIV escapes not by mutating the common epitope, but by high glycosolation? A virus that doesnt have to suffer a loss of infectivity by this glycan shield is just selected out-doesnt this negate the premise of vaccines against HIV?
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What is your opinion of George Shaw's (a leader whose opinon I trust) observation that even with neutralizing antibodies present, HIV escapes not by mutating the common epitope, but by high glycosolation? A virus that doesnt have to suffer a loss of infectivity by this glycan shield is just selected out-doesnt this negate the premise of vaccines against HIV?
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