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fermata1027 karma

It’s topical, ya?

  1. Do you know why the oral formulation isn’t efficacious for PN? Presumably diabetics with PN & comorbidities that this drug treats could just get a Rx & kill 2 birds with one stone (pill) but that’s not the case, right?

  2. Does your lotion/cream/ointment have a similar saftey profile to antimuscarinic agents? If it penetrates the skin effectively to target the nerves then how does it not get into circulation?

fermata1025 karma

Does your compounding recipe have excipients that help skin penetration? How can it have a local effect but not travel throughout the bloodstream? This is confusing me.

fermata1022 karma

Since the drug is for nerve regeneration not for pain - It does beg the question; were patients (or mice) in your trials taking concomitant gabapentin or Lyrica?