Highest Rated Comments

denzil_holles371 karma

Those patents are expired. Manufacturing good lego parts is difficult.

denzil_holles3 karma

Hi Dr Strid, in your paper you write:

How IgE inhibited tumor growth in our model remains to be determined; however, it required expression of FcεRI, and mast cells were not essential, which would suggest it might involve soluble factors and/or cytotoxicity mediated by basophils.

Can you suggest/guess a mechanism by which IgE assists in anti-tumor effects? My impression is that IgE is mostly an anti-parasitic antibody, and that cell-mediated immunity via Th1 CD4+ cells and natural killer cells were responsible for immune surveillance of cancer.

Thank you in advance for reading/answering my question.

denzil_holles1 karma

Very cool! Thank you so much