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broken_sony2 karma

Has anyone yet figured out what, exactly, properly folded PrP does? I had to do a couple of papers/presentations on prions way back in school, and all that was known at the time was that its multiple histidines lent it an affinity for nickel and copper, and that knockout mice without the gene demonstrated no noticeable deficiencies.

Also, people were always arguing with me about the pronunciation of prion. I called it “pree-on”, as an early reference I came across spelt it out. Lots of others though (including professors) insisted it’s “pry-on”, and to this day I still here some scientists call it that. So which is it, exactly?