barbarian818

I'm currently experimenting with psilocybin microdosing to treat depression and anhedonia.

When I started this, there seemed to be early results that supported the idea. Small samples, a lot of anecdotal information. Not much peer reviewed material, but very encouraging all the same.

Since then, I've seen other reports that any beneficial effect might just be the placebo or expectancy effects at work.

So, what's the current understanding in the scientific community? Has it reached a consensus either way?

Thank you.

FWIW; I think I'm seeing a small improvement in certain specific symptoms of depression, but no effect on the anhedonia.

I know the feeling of not wanting to use what seems like your last hope.

I haven't tried a full trip. I have a history of what doctors call a paradoxical response to certain psychoactive medications. Basically, anything with a hypnotic effect may instead trigger bad hallucinations and major aggression.

So I hesitate to take a full dose

I know. Right now I am doing 200 mg every other day. I plan on staying at that level for at least 6 months before making changes.

My big concern right now is on potency and varying chemistries. I know cannabis can have very different effects depending on the exact strain. I assume that shrooms are similar to that.

Plus, it's my understanding that there is a lot of variation in potency within a strain or even with the same batch

Where I am, I can't consistently get the same strain and there's no chance of having an assay done to gauge potency.

What do you do in law suit settlements where the other sides initial offer seems insultingly low? My annoyance wants me to then *increase* my asking settlement, but I'm given to understand that this "isn't done".