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atcg01011 karma

Thank you for your insightful response.

One follow up question: You mention that “most of the studies are about questions that are not of the most important consequence for us” which I agree with. Are there any important questions that you can think of that would be interesting to explore via an aggregate n-of-1 study?

atcg01011 karma

Many thanks for doing this Dr. Galea

With the ongoing digitization of health care do you think there is room for single and aggregate n-of-1 studies in clinical care and clinical research? It’s a model that has gained a “cult” following over the past couple decades but has yielded minimal real world value and I’m curious as to whether or not this is due to lack of value in the actual n-of-1 trial model or if it is due to the cost and logistical obstacles that still exist in creating and running these studies.