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How do admissions work for masters programs that are unrelated to an applicant's undergraduate major?

I'm curious about the computer science masters program at U of R, but my undergraduate degree is in biotechnology and my masters is in microbiology. I'd like to earn a degree in computer science so I'm better equipped to analyze large data sets that come from genomics studies.

I'm assuming I'll need to fulfill some required coursework before I can enter the program. Do I need to apply and be accepted into the undergraduate computer science program and then switch to the master's program if I'm accepted? How does taking the prerequisites for a graduate program work if I'd like to take them at University of Rochester?