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__shamir__8 karma

Yeah, just buy visbiome, that's what vsl #3 in the research literature actually is. It seems like a typical "dispute between the original scientist and the company he contracted to produce at scale" scenario, and in such a scenario you almost always want to go with the scientist :)

__shamir__7 karma

What? No you're totally wrong. What is referred to as VSL #3 in the medical / research literature is what is now sold as Visbiome. Visbiome (FKA #3) is a blend of those specific 8 strains. If someone is selling a probiotic that has, say, Lactobacillus paracasei, but it's not specifically https://gsrs.ncats.nih.gov/app/substance/79e0d4a6-5de3-460b-a1eb-5ce9bcb2e429, then they're not selling the true "vsl #3" (visbiome) formula.

Maybe I misunderstood your point but it sounds like you're saying that the visbiome.com website is mentioning some unrelated lawsuit as a way to falsely market their product, when really what they're saying is "hey we ARE the real thing, and anyone else is selling a knock-off made via a different manufacturing process"

That site literally sells the original formulation of VSL3

Again, this just shows your total ignorance of the subject. The site sells visbiome, which up until January 31, 2016, was sold by that same organization under the name vsl #3, before the whole legal dispute resulted in them needing to clearly differentiate.

Visbiome is vsl#3, which is what all the research is on. If you want the probiotic that has been extensively researched, you buy visbiome, because that's what any study mentioning "vsl #3" is actually talking about


I've already wasted way too many words on what should be pretty straightforward (but your comment was just so horribly wrong that I feel like I need to overexplain), but if you had read the link you replied to you would understand it crystal-clear:

The jury’s finding of false advertising relied upon formidable evidence presented to them that the new version of VSL#3, which is manufactured in Italy, is materially different in composition and efficacy from the original De Simone Formulation manufactured in the United States. And, as a result, VSL#3 can no longer be associated with the rich clinical history that applies to the original De Simone formulation. As of the time of trial, VSL Inc. had not completed a single study on its new formulation showing it performs the same as the original formulation. In this case, the jury unanimously found that the distributors were liable for false advertising, based on overwhelming evidence which showed that they misrepresented new VSL#3® to be the same as the original, which was made with the De Simone Formulation.

__shamir__4 karma

FWIW I don't have ulcerative collitis or IBS or anything like that, but I've been taking 1-2 capsules of visbiome (fka vsl #3) daily for a few years now, and have found that the combination of visbiome and daily psyllium husk fiber makes pooping amazing. So it's been working great for me.

Pretty much all probiotics have the drawback that they only work for a few days before dying off, thus why you need to keep taking them. Only something like a fecal transplant from someone with healthy gut micriobiota will actually stick around long-term.

__shamir__4 karma

I find it a little bizarre that neither your comment nor your blog post talk about the benefits of xylitol consumption. Yes, chewing gum stimulates saliva production which is massively important, but xylitol itself is incredible at fighting bacterial biofilms (plaque), altering the microbiome, etc.

That is to say that I think someone reading your comment or blog post would walk away with the impression that xylitol is just a way to sweeten your gum without it actually being sugar. But the xylitol itself is very important for fighting plaque, maintaining a healthy microbiome, and remineralization.

Is there a reason your blog post doesn't go into that? Xylitol's one of the most miraculous oral health compounds we have (and has some GI benefits too but I digress)

__shamir__2 karma

my understanding is fecal transplants can actually fix the problem long-term (or at least medium-term), whereas oral probiotics only work for a few days or couple weeks at most, before the probiotics inevitably die off