Yazars

Has anyone said whether health screening for things like cancer with mammograms should be the same or for you or different compared to other women? That is, I don't know if people with AIS have different guidelines for health screening.

How long have you been advised that you should/will take estrogen for? That is, would you stop estrogen around 50 years old since that is when many women become menopausal, or would you continue indefinitely?

Thank you for answering my question and for sharing your experiences. May you have good health and lots of happiness moving forward :)

How did you develop your foundation in cooking? That is, how much of it was self-taught, family influence, and/or formal or professional training despite being young?

There are only a few established roles for any kind of immune-based treatment for castrate resistant prostate cancer.

1. It's not T-cell therapy, but Sipuleucel-T, also known as Provenge is an FDA approved option which can be used for people with asymptomatic or minimally symptomatic castrate resistant prostate cancer.

2. Anybody with solid tumors which are microsatellite instability-high (MSI-H), mismatch repair deficient (dMMR), or tumor mutational burden-high (TMB H) (≥10 mutations/megabase (mut/Mb)) are eligible to receive Pembrolizumab, also known as Keytruda as part of its so-called tumor agnostic indication. A modest percentage of people with castrate resistant prostate cancer are found to have these characteristics.

Therapies such as CAR-T for prostate cancer are at the clinical trial phase of development.

Can you please comment about the different characteristics and biological effects of PD-1 antibodies such as pembrolizumab and nivolumab vs. PD-L1 antibodies such as atezolizumab, avelumab, and durvalumab?