WalnutSoap

Oh, you mean DAVID CAGE mode?

Hi Pete! In 2020, my mum (in her early 60s) was told by doctors that a previously treated melanoma had spread through her body. This was at the height of the pandemic, where patients were unfortunately waiting longer than usual for treatment.

My mum was incredibly active - she ran daily and cycled 10 miles to and from work each day but by mid 2020 she was barely able to get around - some part of the cancer had created fluid which pressed on her stomach/gut, and she could hardly walk. Eventually though, she was given immunotherapy and nearly instantly she experienced a massive improvement in her quality of life - she was able to run and cycle again, and most importantly, she was happy, for a good six months or so.

Unfortunately towards the end of 2020, her health started rapidly declining again, and she passed away in early 2021. It was an immense loss, which I still feel today, but I’ll always be grateful for the six months of so of extra time that I got with her, where she was happy and enthusiastic about life. So thank you for the work you do on immunotherapy, because it was single-handedly responsible for giving me that time.

Regarding my questions, I have two:

• Is my mum’s experience (rapid improvement in health/quality of life, followed by a sharp downturn) a common experience with immunotherapy? Is it that patients bodies get used to the treatment eventually? And if so, is this something that folks like you are actively looking to solve?

• Is there somewhere I can donate to that will help fund immunotherapy research and development?

Thank you again for your work, really.

"This one time, I traded my house with some idiot for this sweet bear pen. Worth it"

I cant see it being a problem since it just means it becomes more visible at night, which is a good thing. Glow in the dark paint wouldnt be blindingly bright.

How the hell did you ever think up The Milkman. That stuff lingers man, I've never forgotten it.