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TruPotency_Science1812 karma

CBD might possibly be beneficial on many therapeutic fronts. Although the only FDA approved medication of pure CBD is Epidiolex that is prescribed for seizures (Lennox-Gastaut Syndrome and Dravet Syndrome). Sativex is not available in the US but is a 1:1 THC:CBD available in other countries for spasticity and pain.

Here are a couple of reviews of what it might be good for:
* neuro/psychiactric: Psychiatric disorders like anxiety, depression, schizophrenia and more. Potentially mechanism related to serotonin, PPAR gamma, and a broad variety of other targets.
* anxiety: Anxiety is one big area that CBD might have benefits. Whether it is generalized, social, OCD, PTSD, and more, the data looks promising, but not many clinical trials yet.
* pain 1. This is cannabis-based medicine, but they talk about CBD as well. The lab I worked in focused on pain research and I believe CBD can be beneficial for multiple types of pain.
* pain 2 : CBD may be good for pain and inflammation related to osteoarthritis.
* inflammation: CBD is good for inflammation through potentially a broad variety of actions.
* epilepsy: This one is the most apparent since we have the FDA approved medication Epidiolex.
* many more issues like nausea: CBD might also be useful for nausea, blood pressure, insulin metabolism, reducing tumor growth (*added note from a comment below -- a suggestion of reducing tumor growth does not mean a cure for cancer, although there is ongoing research with CBD and other cannabinoids in oncology), and other diseases and disorders. Although I want to stress more research needs to be done.

Edit: spelling

EDIT 2: I wanted to add potential benefits for those with substance use disorder (e.g. alcohol or opioids) and there are many current and past clinical trials - https://clinicaltrials.gov/ct2/results?cond=&term=cannabidiol&cntry=&state=&city=&dist=

EDIT 3: Since this is the top comment I wanted to post an additional resource. Although not 100% CBD based, it is cannabis-focused and contains a lot of great information about CBD, including the opening talk "The Endocannabinoid System: The Biological Foundation of It All" and a wonderful Canadian neurologist whose talk is titled "Pediatric Epilepsy: Novel Cannabinoid-Based Treatment". https://be.arizona.edu/iics

TruPotency_Science939 karma

We do not think CBD and THC act on the body in similar ways. The general thought now for CBD is actually consistent everyday use would be the best for symptom relief.

TruPotency_Science869 karma

The best thing you can do is to make sure a product has a certificate of analysis (COA). This shows that the product was tested at an analytical laboratory and should have what the label states. Although there is a little gray area there. Labs are known to alter COAs for customers for “correct” results.

That is one reason we double check all the products on our site, because some companies have COAs, but they’re actually falsified or the COA is for the isolate used and not the final product. There is also a lot of variance from lab to lab in the quality of results. We really need better regulation, so we do not have to worry about the quality of product testing information.

The main inherent danger comes from having THC in a THC free product for those trying to avoid that, or there are other harmful chemicals like pesticides or synthetic cannabinoids.

TruPotency_Science733 karma

I think some of the biggest myths are that CBD will cure X disease. At most, we think CBD might help with symptoms of various ailments, but a cure for Parkinson’s, Alzheimer’s, anxiety, and more is probably not the case. I would be more than happy to eat my words as more data and research comes in though.

TruPotency_Science670 karma

There can be heavy metals, pesticides, mycotoxins, and other harmful chemicals. Generally, the labeled amount of CBD is just way off (e.g. 500 mg on the label, but tested for less than 300 mg). We most often see missing cannabinoids or terpenes from the label (e.g. CBG claim yet no tested CBG) or cannabinoids that shouldn’t be there (e.g. d-9-THC in an isolate product).