Highest Rated Comments


ThryveInside117 karma

Just my dignity.

ThryveInside33 karma

Get a new mother-in-law.

ThryveInside26 karma

If you are referring to Fecal Microbiota Transplant (FMT) then yes, there are a lot of scientific backing on it's efficacy on Clostridium Difficile which is a stomach bug that takes over someone's gut after a round of antibiotics. It's a serious infection that is >90% efficacious in curing the problem.

Otherwise, there's been a lot of research showing the importance of a healthy and balanced microbiome and that "eating poop pills" has been helpful in a number of conditions; however, at this time we need more data / evidence.

I would check out OpenBiome (they are one of the largest stool banks), who provide poop pills. Also Dr. Tom Louie who was the pioneer in developing a triple encapsulated FMT pill. Seres Therapeutics is another company developing their own FMT pills, but failed in phase 2 clinical trials because they only extracted spores of bacteria vs. the entire microbiome (bacteria, yeast, viruses, etc...)

ThryveInside15 karma

That's a fair question and I don't see you trolling. Thanks for asking.

I'd say that there are a whole host of studies regarding the efficacy of probiotics (see below). That said, they haven't been as rigorous with large sample sizes to move them from "psuedoscience" to "science". Partly, because funding just isn't there. Probiotics aren't a billion dollar blockbuster drug that pharmaceuticals will back.

The question is "why our product and why not Kombucha"? We'll we encourage everyone to try homemade probiotics (as you see above, I tell people to make Kefir Milk). Natural methods of improving your microbiome is part of the test we offer (in terms of diet recommendations), so we encourage trying those as well.

I'll be frank, our probiotics have gone through in vivo, in vitro, and small human sample sizes to show efficacy. However, we'd like more opportunity to learn and research more. You can think of our product also as one of the largest probiotic research projects and everyone is helping to contribute!

Source:

-O’Mahoney L et al. Lactobacillus and Bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology. 2005. 128: 541-551

-Nobaek S et al. Alteration of intestinal microflora is associated with reductions in abdominal bloating and pain in patients with irritable bowel syndrome. The American Journal of Gastroenterology. 2000. 95(5): 1231-1238.

-Niedzielin K. A controlled, double-blind, randomized study on the efficacy of Lactobacillus plantarum 299V in patients with irritable bowel syndrome. European Journal of Gastroenterology & Hepatology. 2001. 13(10): 1143-1147.

-Ouwehand et al., Probiotics reduce symptoms of antiboitic use in a hospital setting: A randomized dose response study. Vaccine. 2014. 32(4):458-463

-Kekkonen et al., Probiotic intervention has strain-specific anti-inflamatory effects in healthy adults. World J Gastroenterol. 2008. 14(13):2029-2036

-Kim HJ et al. A Randomized controlled trial of a probiotic combination VSL #3 and placebo in irritable bowel syndrome with bloating. Neurogastroenterology and Motility. 2005. 17: 687-696.

-Kajander K et al. A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6-month intervention. Alimentary Pharmacology & Therapeutics. 2005. 22: 387-394.

-Bausserman M, Michail S. The use of Lactobacillus GG in irritable bowel syndrome in children: a double-blind randomized control trial. The Journal of Pediatrics. 2005.147(2): 197-201.

-Niv, E et al. The efficacy of Lactobacillus reuteri ATCC 55730 in the treatments of patients with irritable bowel syndrome – a double blind, placebo-controlled, randomized study. Clinical Nutrition. 2005. 24: 925-931.

ThryveInside13 karma

“All disease begins in the gut.” – Hippocrates.

On a serious note, there has been an explosion of research showing that the gut microbiome (trillions of bacteria, yeast, and viruses) are related to a whole host of modern and chronic diseases. Such as, Autoimmune diseases, irritable bowel syndrome, allergies, etc... Furthermore, we've started to see an extinction of microbes in the guts of people living in western civilization due to antibiotics, low-fiber diets, lifestyle, etc... These microbes are essential to synthesizing vitamins, digesting foods, immune regulation, hormone and neurotransmitter production, and many more.

By taking care of your gut, you are taking care of your health & wellness in the long-term and improving quality of life.