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Shishire3 karma
This seems to be related to the concept of Memory reconsolidation, specifically chemical downplay of the amygdala during directed reconsolidation processes. Is this technique statistically more effective than the propranolol and/or sirolimus therapies that were attempted in the early 2010s?
Shishire3 karma
Super fascinating stuff.
How does this interact with the more serious dissociative conditions, i.e., OSDD/DID, etc.? One of the primary issues with similar therapies (e.g. EMDR) in dissociative patients is that it's extremely likely to cause trauma flooding if not done extremely carefully.
We're super interested in this stuff, since we're always looking to improve the quality of our own care, as well as provide useful information to other OSDD/DID systems.
Shishire1 karma
This is kind of why we're cautiously optimistic about this treatment. We've seen research done into other pharmaceutical variations on memory editing (the real kind, not the sci-fi version), and while it looks super-promising, there's a massive number of gotchas and side-effects that have to be carefully controlled for in order for the treatment to be effective.
Memory reconsolidation is a paper that describes something similar, although it's a much earlier application of the general technique of amygdala minimization on reconsolidation processes.
Shishire4 karma
Okay, so it suffers from the same issues EMDR has with regards to trauma flooding.
On the other hand, since it is an invasive medical procedure, there's a significantly higher knowledge level on the interplay with dissociative conditions from the team involved in the treatment.
Awesome, good to know.
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