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PureImbalance203 karma

You seem alright, you would fit right in at /r/freefolk

PureImbalance62 karma

Maybe initially, but it can quickly become a self-inforcing cycle

PureImbalance18 karma

The (to me) elegant idea in this theory is that it responds to a few overlooked things in oncology. One is that for a cell to accumulate mutations (and enough to slowly become a cancer cell) it has to divide. And to divide a lot. And most cells of your body do not divide, they are senescent. The cells that do most of the dividing are stem cells and progenitor cells, thus, statistically, they are the ones that are most likely to become carcinogenic.
Additionally, it is highly elegant because to go from stem cell to cancer, you need fewer mutations than from "normal cell" (differentiated) to cancer, as some properties like self-renewal are already present.
The problem with the research in my opinion is that stem cell research in itself is also still lacking, thus having a lot of questions questions where the answer is that we simply don't know. I think the field will become very important in oncology, and the great thing is that during the trip in the stem cell field, we will find out many things that are also applicable to totally different fields outside of oncology.
If you are interested, here is a paper in which they looked to identify stem cells in the cancer, and while there is valid criticism to the work (e.g. their assumption of graftability into the used mice which filters their result, thereby biasing, and i would mostly disregard the bioinformatic predictions) it is still very interesting. Cancer stem cells is a theory that is not applicable to all cancers, but for some will be very promising.

PureImbalance17 karma

reminds me of the movie "In Time" too

PureImbalance8 karma

hate to break it to you, but nobody currently knows how to actually get two giant spheres of iron to relativistic speeds.