PrecursorNL
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PrecursorNL3 karma
Strongly disagree. I have been on a serious amount of trips in my life, similar to you maybe. Started at 17, 29 now. Studied pharma research, brain and a little while in organic chemistry.
But 2-CB is absolutely not the first thing I'd recommend. A close relative has taken it twice and twice it was a bad experience. And with bad I mean she almost got a full psychosis.
If you read this and want to try psychedelics please consider the potential harm too. It's all fun and games until it's not. Prepare well and take it slow. Have people around. 2-CB is a pretty strong drug. Personally I'd rather recommend taking LSD as a first psychedelic drug, it's much easier to dose even if you just have paper tabs. Take a quarter or half tab and see if you like it before going on a crazy bender and ruining all future experiences because you started with a bad trip. Also be with friends. Friends are important :)
PrecursorNL2 karma
Shame this didn't get a comprehensive answer or any of the responses below.
I have done some research on endocannabinoids in my time as master student in a group developing small molecule inhibitors. They were usually tested in vitro in pretty basic conditions and then straight in mice. I don't know if any made it into trials and tbf they weren't all for cancer either.
Nevertheless what I did learn is that these compounds, and here I mean cannabinoids, and specifically some of our own endocannabinoids, really do seem to have very interesting effects. How we could actually harbor those would possibly be by interacting with the synthesis and degradation of said endocannabinoids. They are really quite inherent to our system, if you consider that many are lipid signaling molecules. In fact some of these are the first signaling molecules we get in cells since lipids that are related literally make up the cell walls. They are essential for life and are the first to develop in the fetus. I'm getting a little off track but my point is that there is definitely some merit in researching this, although we shouldn't focus on weed as an all-in-one solution because it's made up of hundred+ active compounds. Hopefully therapies will come that play into lipid signaling and these will help to understand what cannabinoids actually do.
Remember we only call them cannabinoids because we found them in a plant. We call the receptors we found to be activated by these plants cannabinoid receptors. Obviously, this is extremely outdated (!!!). We do not have receptors in our bodies tailored to a plant...... They respond to many other compounds, most notably lipids that we called endocannabinoids because they happen to activate the receptors we found after the plant. And what's even more interesting is that we're still finding new receptors that we categorize in this group. I really think that the cannabinoid research still has a lot of discoveries to be made, as soon as the public realizes that it's not all about weed
PrecursorNL2 karma
How do I get into the gaming field as an audio professional? Bonus points, I have a back ground in neuroscience and pharmaceutical research so I'm missing the right network.. but I'm a producer for 12 years and have been classically trained since the age of 5
PrecursorNL1 karma
How did you get into composing (for gaming)? Did you have any formal training? And who would you go to if you were a starter trying to land a gig? (let's say you've been producing for 12 years..)
PrecursorNL3 karma
What did it feel like?
Do you remember anything about the moment?
Did your life flash in front of your eyes?
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