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A very recent study by Taurah et al. indicates that MDMA use results in widespread behavioral deficits when compared to other drug users, and that alarmingly, these deficits did not go away even after a prolonged period of abstinence. When taken together with evidence in animal models that any substantial MDMA usage causes irreparable damage of serotonergic neurons, it appears that MDMA use can result in the selective yet permanent death of these neurons even in humans.

What methods have you utilized to minimize the damage and maximize the benefits of these psychedelics in your research trials?