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The thing about hybrids not "breeding true" is not a big problem. Often the f2 and later progeny of F1 hybrids still have higher yields and disease resistance than heirlooms. There is much often parroted misunderstanding regarding this. It would be easy to take the segregates and just turn them into stabilized strains in a few growing seasons, creating new "heirlooms".

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Well this depends on species. Crops are generally lumped in 2 categories basic inbreeders(ex..tomatoes) and basic outbreeders(ex..Maize) you can plant inbreeders save seed and rarely if ever have to worry about inbreeding depression. Basic outbreeders require outcrossing between a certain size population in order to avoid inbreeding depression. So as long as you maintain a high enough plant population yes the progeny of F1 hybrids will be a healthy crop for unlimited years. In fact because the progeny of hybrids will have more genetic diversity compared to stabilized strains you would have a better chance of avoiding inbreeding depression. There are of course exceptions to the rule such as if the hybrid was made with a parent having male cytoplasmic sterility, amongst others

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What do you think about my idea that the solution to fermi's paradox is that there is a convergent evolution whereby all lifeforms that achieve digital technology eventually achieve full conversion to near planck scale as possible computronium which explains all the dark matter in the universe. Dark matter is just computronium.