Ilikescienceandstuff

Biochemistry student here, don't scare the people with what they don't understand. I mean one of the most basic reactions in glycolysis switches to make NADPH during stress from G-6-P. Then it's just oxidation to make NADP. There's so much going on in the biosynthetic pathway it's easy to make claims like this and be correct, because it does deplete NADP+ stores, but at the same time the system corrects the imbalance, so it isn't really representative of what's going on.

Have you seen the phenomenon in a lab/aquarium with a previously infected organism? What's the physiologic mechanism that drives the one leg in the other directions past structural damage feedback points?