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From the philosophical standpoint of whether violent offenders should be held responsible for their actions even if predisposed, I believe that they should; However, it would be more along the lines of treatment similar to how murderers that are dubbed insane will get psych treatment instead of going to jail. The the only purpose for punishment is to remedy the offender's behaviour so that the action will not occur in the future.

If bad biology is to blame for actions, then it needs to be addressed just like any other disease that prevents people from functioning in a normal society.