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Chonky-Bukwas8 karma

Methotrexate is an immunosuppressant. immunosuppressants and increased chance of infection go hand in hand together.

Chonky-Bukwas8 karma

wow! so it looks like they have a less severe response because their immune system isn't able to react as strong.

" reduced severe inflammatory reactions as a result of inhibited TNFα, lowered IL6, and increased T regulatory cells. According to these findings, methotrexate appears to be a suitable treatment option for patients who need immunosuppressive medications during the COVID-19 pandemic."

eh, a huge problem with this study is the tiny sample size. that's great that it works for some patients, but that sample size is REALLY small. a shitty part of autoimmune disease is that methods that work for some people are devastating to others.

"Methods: A total of 35 participants, including 14 patients taking methotrexate and 21 patients with normal immune function,"

Chonky-Bukwas5 karma

Would your average person be better off donating to lobbyist groups instead of politicians?

Chonky-Bukwas3 karma

thanks!