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COULD_YOU_PLZ_SNIFF5 karma

Awesome question... too lazy to dive into the research, but in my experience, we throw steroids at the immune-related adverse events of checkpoint inhibitors.

EDIT: Here is a paper that outlines possible treatments. Approach to therapy depends heavily on severity of the reaction. If not responsive to steroids, other agents (eg TNF blockers) can be considered.

COULD_YOU_PLZ_SNIFF3 karma

I think the answer is yes it can happen, but usually it remains seronegative.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127444/

COULD_YOU_PLZ_SNIFF1 karma

Thanks for this! What is the significance of the gd T cell vs ab T cell population?

COULD_YOU_PLZ_SNIFF1 karma

Hello,

Can you please explain what exactly γδ T cells are?

Thanks!