AmanitaMakesMe1337er

I have heard many anecdotal reports of this being very effective. I hope it helps you!

I have been struggling with depression for a couple of years. I've been wanting to try LSD/psilocybin for about 6 months now, but am worried about potential interactions with Fluoxetine. I have found very little to no research on this, and very few anecdotal accounts. I am aware Fluoxetine works by inhibiting the reuptake of serotonin, however I am hazy on the complicated pharmacology of LSD/psilocybin.

Do you take your research subjects off their medication before administering psilocybin? Do you have any knowledge of interactions between these substances?