IAmA "refractory" Crohn's patient who has taken nearly every FDA-approved drug for the disease. At one point, I was being screened for a stem cell clinical trial. Today, I have multiple years in remission, thanks to medical marijuana. AMA!
I was diagnosed at 16 and was immediately started on prednisone and azathioprine, due to the severity of the inflammation in my terminal ileum. Those didn't do the trick, so we started Remicade. Remicade worked nicely for a few months, then I lost response. We then jumped to Humira, which reduced my symptoms, but was never remission-inducing.
At this point, I went to college and switched doctors. He got me to try Tysabri, which was removed from the market for two years because of a link to causing PML, an extremely serious brain infection, but was allowed back on the market under a severe federal monitoring program. Needless to say, Tysabri didn't reduce my symptoms either.
I was then at a wall because the only other TNF blocker, Cimzia, had about a 10% chance of inducing remission, probably less. I opted to try screening for a stem cell trial that my doctor was heading at the time.
During this entire three years of medication hopping, I was obviously miserable, running to the bathroom constantly, being nauseous, losing weight, etc. There was even an 18 day period of time where I couldn't keep down any solid food and was living on Jamba Juice while we tried different anti-emetics.
That was when I tried marijuana to control nausea and vomiting. It worked. I begged my doctor to also prescribe Marinol, which he did, and three years later, I'm still in remission. AMA!
EDIT: I DO NOT CLAIM TO BE CURED. THIS IS A CHRONIC DISEASE. I AM IN REMISSION. THERE IS A DIFFERENCE.